Cenforce 100 (sildenafil citrate) and Tadalafil (often sold as Cialis) are both PDE5 inhibitors used to treat erectile dysfunction (ED), but they differ in duration and onset of action. Cenforce 100 typically works within 30–60 minutes and lasts for about 4–6 hours, making it suitable for planned sexual activity. Tadalafil, on the other hand, takes effect in about 30 minutes but can last up to 36 hours, offering more spontaneity. Tadalafil is also approved for daily use and treating benign prostatic hyperplasia (BPH). While both are effective, the choice depends on your health, lifestyle, and doctor’s recommendation.